Kidney transplant operation involves taking out a kidney from the body of a person (either living or deceased donor) and transplanting it surgically in the body of another patient whose kidneys have failed. Patient with end stage kidney failure have two choices, either lifelong dialysis or kidney transplantation. Transplantation offers better quality of life, better long term rehabilitation and is more cost effective than lifelong dialysis. Lisie has highly specialized nephrologists, urologists and transplant surgeons, who work as a close knit unit and has produced the best outcomes in kidney transplantation.
End stage renal disease (ESRD) is diagnosed by blood tests that show the blood urea and creatinine levels to be elevated above normal, and scans (ultrasound scan, usually) that shows the kidneys are shrunken and replaced by scar tissue.
The residual function in the scarred or irreversibly damaged kidneys can be calculated by a formula easily available on the internet called the GFR calculator ( there are 2 widely used formulas: MDRD and Cockroft-Gault) that takes into account the lab values and age and height of the individuals.
When GFR falls below 20 or the patient is very symptomatic due to deranged renal function, it is time to consider RENAL REPLACEMENT THERAPY. This means dialysis and /or kidney transplant.
The actual operation of kidney transplant is not very stressful to the patient. The heart has to do extra work to meet the demands of the new organ and making sure the heart is able to cope with increased workload is a major part of the evaluation before surgery.
Dialysis and skillful management by experienced Nephrologists make the operation very safe. Most transplant centers report less than 5% mortality and normal function of the transplanted kidney is achieved in over 90% of patients.
b. Anti-rejection medicine
Anti rejection medicines are required lifelong. The number of medicines and the doses are maximum in the first year and require close monitoring. After this, with modern transplant medicine, the side effects are minimal and patients lead a normal life with minimum increased susceptibility to infections and tumors that require lifelong follow-up with the Nephrologists.
Keep all other organs in good condition, especially heart and lungs. Smoking increases the risk of death and graft failure. A sedentary lifestyle with no exercise result in poor cardiac reserve and risk of death. Exercising for 1 hour on every non-dialysis day is important. Weight control is critical and staying within 10 Kg of ideal body weight makes chances of a good long term outcome very high.
Post OP ICU stay up to 1 week and 3 weeks in hospital is the normal practice.
Patient survival >95% and Graft survival > 90%.